Synthesis and Antibacterial Activity of Azo-Sulfa-Based Disperse Dyes and Their Application in Polyester Printing

Abstract For conjugating sulfa drug moieties with Schiff’s bases scaffold in the same build through an azo linker to take advantage of bioactive feature both motifs, we designed and synthesized a series disperse dyes. The target dyes, methyl 2-( E -2-hydroxy-5-(( )-(4-sulfa-derivative) diazenyl)benzylidene) hydrazine-1-carbodithioates 4a – e have been via acidic reaction dyes 3a hydrazine carbodithioate. Structures were clarified based on their spectral elemental analyses. effectiveness was initially tested as antibacterial toward Staphylococcus aureus ATCC 6538-P Escherichia coli 25933. Dyes that proven be effective against bacteria used print polyester fabrics. color properties fastness counting washing, perspiration, light, rubbing, sublimation also examined. printed fabrics evaluated for activity colony-forming unit (CFU) technique. Fabric samples treated 4c , 4d 4b had promising anti-Gram-positive activities S. aureus. Whereas 4c- 4d- -treated exhibited moderate anti-Gram-negative test bacterium E. .